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An undated photographic portrait captioned ‘Florence Buchanan’ in Lilian Adam Smith’s privately printed 1941 Buchanan family memoir. A Memoir of the Buchanan Family, National Library of Scotland, Acc.9446/400.

Florence Buchanan: the pioneering physiologist whose face was lost to history

Florence Buchanan helped transform the study of the nervous system, yet no authenticated portrait of her was known until now.
Symptoms can return despite continued antidepressant treatment, but this does not necessarily mean the body has become tolerant to the medicine. Vitalii Vodolazskyi/Shutterstock

Why antidepressants can stop working after initially helping

Antidepressant tachyphylaxis describes the loss of a treatment response that was once effective. Here’s what scientists know so far.