Cells degrade and recycle damaged parts of themselves through a process called autophagy. When this “self-devouring” goes awry, it may promote cancer and neurodegenerative disease.
Articles on Drug targets
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Every cancer is different. Grouping cancer mutations by their structure and function could help make treatments more personalized.
Kinases are cellular control switches. When they malfunction, they can cause cancer. The coronavirus hijacks these kinases to replicate, and cancer drugs that target them could fight COVID-19.
Top contributors
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Postdoctoral Scholar of Pharmacy and Pharmaceutical Science, University of California, San Diego
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Professor of Pharmacy and Pharmaceutical Sciences, University of California, San Diego
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Assistant Professor of Thoracic & Head and Neck Oncology, The University of Texas MD Anderson Cancer Center
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Professor and Director of Quantitative Biosciences Institute & Senior Investigator at the Gladstone Institutes, University of California, San Francisco