cfDNA PPV Calculator

Medical

Free · Designed for iPad. Not verified for macOS.

Estimate PPV and NPV for common cfDNA screening conditions using Bayesian probability. Editable test performance and prevalence inputs. This Cell Free Fetal DNA PPV Calculator estimates positive predictive value (PPV) and negative predictive value (NPV) for prenatal cell-free DNA (cfDNA) screening using Bayesian probability. Conditions supported: • Trisomy 21 • Trisomy 18 • Trisomy 13 • Monosomy X (45,X) • 47,XXY • 47,XYY • 47,XXX For autosomal trisomies, pretest probability may be derived from maternal-age population risk tables (midtrimester risk by age at term). For sex chromosome aneuploidies, pretest probability can be entered as population prevalence (1 in N). Sensitivity and specificity are user-editable to reflect lab-specific performance. This app is for screening support and educational use. It does not provide a diagnosis. Positive screening results should be confirmed with diagnostic testing and clinical correlation.

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The developer, David Deschamps, indicated that the app’s privacy practices may include handling of data as described below. For more information, see the developer’s privacy policy .

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    Provider
    • David Deschamps
    Size
    • 678.9 KB
    Category
    • Medical
    Compatibility
    Requires iOS 18.4 or later.
    • iPhone
      Requires iOS 18.4 or later.
    • iPad
      Requires iPadOS 18.4 or later.
    • Mac
      Requires macOS 15.4 or later and a Mac with Apple M1 chip or later.
    • Apple Vision
      Requires visionOS 2.4 or later.
    Languages
    • English
    Age Rating
    16+
    Copyright
    • © 2026 David Deschamps